From the College of Dental Medicine…

July 2023 Research Highlights reported by the College of Dental Medicine.


Toshihisa Kawai DDS, Ph.D.

Noteworthy publications out of Dr. Toshihisa Kawai‘s laboratory. NSU faculty and student authors are bolded:

1) Porphyromonas gingivalis outer membrane vesicles exacerbate retinal microvascular endothelial cell dysfunction in diabetic retinopathy.
Huang S, Cao G, Dai D, Xu Q, Ruiz S, Shindo S, Nakamura S, Kawai T, Lin J, Han X. Front Microbiol. 2023 May 11;14:1167160. doi: 10.3389/fmicb.2023.1167160. eCollection 2023. PMID: 37250057 [Journal IF 6.1]

2) Soluble Sema4D cleaved from osteoclast precursors by TACE suppresses osteoblastogenesis.
Ishii T, Ruiz-Torruella M, Kim JY, Kanzaki H, Albassam A, Wisitrasameewong W, Shindo S, Pierrelus R, Heidari A, Kandalam U, Nakamura S, Movila A, Minond D, Kawai T. J Cell Mol Med. 2023 May 11. doi: 10.1111/jcmm.17416. Online ahead of print. PMID: 37170687 [Journal IF 5.3]

3) Extracellular Release of Citrullinated Vimentin Directly Acts on Osteoclasts to Promote Bone Resorption in a Mouse Model of Periodontitis.
Shindo S, Pierrelus R, Ikeda A, Nakamura S, Heidari A, Pastore MR, Leon E, Ruiz S, Chheda H, Khatiwala R, Kumagai T, Tolson G, Elderbashy I, Ouhara K, Han X, Hernandez M, Vardar-Sengul S, Shiba H, Kawai T. Cells. 2023 Apr 8;12(8):1109. doi: 10.3390/cells12081109. [Journal IF 7.6]

4) Perfluorooctanoic acid-induced cell death via the dual roles of ROS-MAPK/ERK signaling in ameloblast-lineage cells.
Fujiwara N, Yamashita S, Okamoto M, Cooley MA, Ozaki K, Everett ET, Suzuki M. Ecotoxicol Environ Saf. 2023 Jul 15;260:115089. doi: 10.1016/j.ecoenv.2023.115089. Epub 2023 Jun 2. PMID: 37271104 [Journal IF 7.1]

5) In Situ Raman Analysis of Biofilm Exopolysaccharides Formed in Streptococcus mutans and Streptococcus sanguinis Commensal Cultures.
Pezzotti G, Ofuji S, Imamura H, Adachi T, Yamamoto T, Kanamura N, Ohgitani E, Marin E, Zhu W, Mazda O, Togo A, Kimura S, Iwata T, Shiba H, Ouhara K, Aoki T, Kawai T. Int J Mol Sci. 2023 Apr 3;24(7):6694. doi: 10.3390/ijms24076694. PMID: 37047667 [Journal IF 5.3]

6) Preliminary analysis of the buccal mucosal fungal microbiome in oral lichen planus patients.
Du G, Jiang X, Han X, Pan L, Tang G. J Oral Pathol Med. 2023 May 30. doi: 10.1111/jop.13439. Online ahead of print.PMID: 37252860 [Journal IF 3.5]

7) The Lysyl Oxidase G473A Polymorphism Exacerbates Oral Cancer Development in Humans and Mice.
Peymanfar Y, Mahjour F, Shrestha N, de la Cueva A, Chen Y, Huang S, Kirsch KH, Han X, Trackman PC. Int J Mol Sci. 2023 May 28;24(11):9407. doi: 10.3390/ijms24119407. PMID: 37298359 [Journal IF 5.3]